منابع مشابه
Optic Atrophy Induced by Chloramphenicol.
CHLORAMPHENICOL is an antibiotic that is used mainly for treating diseases caused by bacteria which are not sensitive to other, less toxic, antibiotics. Some of these diseases entail prolonged courses of treatment and the drug has to be administered for months or even years; the commonest diseases requiring prolonged treatment are subacute bacterial endocarditis, pyelonephritis, and fibrocystic...
متن کاملOptic Atrophy.
BASIC CONSIDERATIONS Optic atrophy is a misleading term which, embedded by tradition and usage, resists precise definition. It is used when there is excessive pallor of the optic disc and is thus a physical sign and not a diagnosis. Since there are many causes of optic pallor, the term is usually reserved for those cases in which there is associated visual defect, either of fields or acuity, in...
متن کاملDominantly inherited optic atrophy.
LEBER'S disease, with its sudden onset in adolescence or early adult life, its rapid course, and puzzling mode of inheritance, has overshadowed other forms of inherited optic atrophy. The early literature contained many cases of "atypical" Leber's disease, but the continued emphasis on the established form, even in the monumental review by Bell (1931), hampered the emergence of other forms as s...
متن کاملDominant optic atrophy
UNLABELLED DEFINITION OF THE DISEASE: Dominant Optic Atrophy (DOA) is a neuro-ophthalmic condition characterized by a bilateral degeneration of the optic nerves, causing insidious visual loss, typically starting during the first decade of life. The disease affects primary the retinal ganglion cells (RGC) and their axons forming the optic nerve, which transfer the visual information from the pho...
متن کاملAn old friend revisited: chloramphenicol optic neuropathy
A 66-year-old woman presented on October 2011 with a 10-day history of painless bilateral visual loss of subacute onset (over 48 h). She also described paraesthesiae of the limbs for a similar duration. She has rheumatoid arthritis, treated with methotrexate (since 2002) and etanercept (2003– 2009), and she required bilateral knee replacements in 2009. Her right knee replacement was revised and...
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ژورنال
عنوان ژورنال: British Journal of Ophthalmology
سال: 1964
ISSN: 0007-1161
DOI: 10.1136/bjo.48.10.567